Publications

Publications by PI Timothy Chang MD, PhD 

View the NCBI bibliography

   Selected Publications   

  • Fu M, Yan, Y, Olde Loohuis, LM, and Chang, TS. Defining the distance between diseases using SNOMED CT embeddings. J. Biomed. Inform. 2023 Feb 2.
  • Fu M, UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group, Chang TS. Phenome-Wide Association Study of Polygenic Risk Score for Alzheimer’s Disease in Electronic Health Records. Frontiers in Aging Neuroscience. 2022 Mar 15.
  • Tracy TE, Madero-Pérez J, Swaney DL, Chang TS, Moritz M, Konrad C, Ward ME, Stevenson E, Hüttenhain R, Kauwe G, Mercedes M, Sweetland-Martin L, Chen X, Mok S-A, Wong MY, Telpoukhovskaia M, Min S-W, Wang C, Sohn PD, Martin J, Zhou Y, Luo W, Trojanowski JQ, Lee VMY, Gong S, Manfredi G, Coppola G, Krogan NJ, Geschwind DH, Gan L. Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration. Cell. Elsevier; 2022 Jan 20;0(0). PMID: 35063084 
  • COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19. Nature. 2021 Jul 8;1–8 
  • Chang TS*†, Ding Y*, Freund MK*, Johnson R*, Schwarz T*, Yabu JM, Hazlett C, Chiang JN, Wulf DA, UCLA Precision Health Data Discovery Repository Working Group, Geschwind DH, Butte MJ†, Pasaniuc B†. Pre-existing conditions in Hispanics/Latinxs that are COVID-19 risk factors. iScience. 2021 Mar 19;24(3):102188. PMCID: PMC7879099
  • Rexach JE, Polioudakis D, Yin A, Swarup V, Chang TS, Sarkar A, Chen L, Huang J, Lin L-C, Seeley W, Trojanowski JQ, Malhotra D, Geschwind DH. Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression. Cell Rep. 2020 Nov 17;33(7):108398. PMCID: PMC7842189 
  • Swarup V*, Chang TS*, Duong DM, Dammer EB, Dai J, Lah JJ, Johnson ECB, Seyfried NT, Levey AI, Geschwind DH. Identification of Conserved Proteomic Networks in Neurodegenerative Dementia. Cell Rep. 2020 Jun 23;31(12):107807. PMID: 32579933
  • Chang TS, Buchipudi A, Fonarow GC, Pfeffer MA, Singer JS, Cheng EM. Physicians Voluntarily Using an EHR-Based CDS Tool Improved Patients’ Guideline-Related Statin Prescription Rates: A Retrospective Cohort Study. Appl Clin Inform. 2019 May;10(3):421–445. PMCID: PMC6584145
  • Chang TS, Patel CB, Keener AM, Keselman I, Jamal NI. Movements Here Today, Gone Tomorrow: Images in Clinical Neurology Case of Hyperglycemic Hemichorea. Neurohospitalist. 2017 Jul;7(3):150. PMCID: PMC5467814
  • Chang TS, Teng E, Elashoff D, Grill JD, Alzheimer’s Disease Neuroimaging Initiative. Optimizing Effect Sizes With Imaging Enrichment and Outcome Choices for Mild Alzheimer Disease Clinical Trials. Alzheimer Dis Assoc Disord. 2017 Mar;31(1):19–26. PMCID: PMC5116001
  • Chang TS, Gangnon RE, David Page C, Buckingham WR, Tandias A, Cowan KJ, Tomasallo CD, Arndt BG, Hanrahan LP, Guilbert TW. Sparse modeling of spatial environmental variables associated with asthma. J Biomed Inform. 2015 Feb;53:320–329. PMCID: PMC4355087
  • Chang TS, Jensen MB. Haemodilution for acute ischaemic stroke. Cochrane Database Syst Rev. 2014;(8):CD000103. PMCID: PMC4181849
  • Chang TS, Lemanske RF, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, Gangnon RE, Page CD, Jackson DJ, Childhood Asthma Research and Education (CARE) Network Investigators. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol. 2014 Feb;133(2):363–369. PMCID: PMC3960405
  • Chang TS, Lemanske RF, Guilbert TW, Gern JE, Coen MH, Evans MD, Gangnon RE, David Page C, Jackson DJ. Evaluation of the modified asthma predictive index in high-risk preschool children. J Allergy Clin Immunol Pract. 2013 Mar;1(2):152–156. PMCID: PMC3811153.
  • Chang T. Personalizing medicine: beyond race. Virtual Mentor. 2012 Aug 1;14(8):628–634. PMID: 23351318.
  • Chang TS, Coen MH, La Rue A, Jonaitis E, Koscik RL, Hermann B, Sager MA. Machine learning amplifies the effect of parental family history of Alzheimer’s disease on list learning strategy. J Int Neuropsychol Soc. 2012 May;18(3):428–439. PMCID: PMC3348337.
  • International Warfarin Pharmacogenetics Consortium, Klein TE, … Chang T, et. al. Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med. 2009 Feb 19;360(8):753–764. PMCID: PMC2722908